Search Results for: program in cellular and molecular medicine
Immune biomarkers predicted COVID-19 severity and could help in future pandemics
Why did some people fall critically ill from COVID-19 and others not? In May 2020, as COVID-19 swept the world, …Read More
A promising target for ALS and other neurodegenerative disorders: Curbing inflammation
When cells recognize a danger, such as an infection, they activate the innate immune system. Sentinel molecules sound an alarm, …Read More
Tim Springer: Scientist, entrepreneur, and mentor
As an undergraduate in 1966, immunologist, biochemist, and biophysicist Timothy A. Springer, PhD, looked askance at science. The Vietnam War …Read More
Unlocking antibody diversity: chromatin loops, V(D)J recombination, and class switching
A new study from the laboratory of Frederick Alt, PhD, of the Program in Cellular and Molecular Medicine (PCMM) at Boston Children’s …Read More
Targeting a rogue T cell prevents and reverses multiple sclerosis in mice
Multiple sclerosis is an autoimmune disease affecting both adults and children. It’s driven by “helper” T cells, white blood cells …Read More
Presidential awardee explores epigenetics via slime molds, worms, and more
Pretty much all of your cells have the same DNA code. Yet they come in an astonishing number of forms. …Read More
Catching platelets with NETs: Neutrophils and deep vein thrombosis
Sea cucumbers have an unusual way of defending themselves. When threatened, they ensnare their foes with sticky threads. Some even expel …Read More
Messenger RNA: A game-changing advance in regenerative medicine
A new way to reprogram ordinary human cells into stem cells, using RNAs, appears safer and much more efficient than current …Read More
Building better antibodies, curbing autoimmunity: New insights on B cells
When we’re vaccinated or exposed to an infection, our B cells spring into action, churning out antibodies that are increasingly …Read More
A journey through the intestine during colitis, cell by cell
Inflammatory bowel disease (IBD), causing devastating abdominal pain, persistent diarrhea, and rectal bleeding, is hard to control with current treatments. …Read More