Archive for big data
A nimbler way to track alcohol use: mining Twitter and Google searches
Large, survey-based studies are a slow, expensive way to collect rigorous public health data. New research, focusing on alcohol use, shows that mining Twitter and online searches could enable public health professionals to get immediate, localized insights, spot emerging trends, and even measure the effects of interventions. “Online user-generated data are fluid and nimble — ... Read More
CHIP-ing away at health and medicine for 25 years: A look back
In 1994, when CHIP was formed, the dotcom boom was just dawning. iPhones and social media (except for the earliest versions) were more than a decade away. Bill Clinton was president. Isaac Kohane, MD, PhD, had just completed a fellowship in endocrinology at Boston Children’s Hospital under the mentorship of Joseph Majzoub, MD. He wanted ... Read More
After GWAS studies, how to narrow the search for genes?
Genome-wide association studies (GWAS) look at large populations to find genes that contribute to common, multi-gene traits like height or obesity. These comprehensive investigations frequently turn up large numbers of tiny genetic variations that show up more often in people who are tall, obese, etc. But this association doesn’t mean the variant actually helps cause ... Read More
Small samples, big data: A systems-biology look at a newborn’s first week of life
The first week of a baby’s life is a time of rapid biological change. The newborn must adapt to living outside the womb, suddenly exposed to new bacteria and viruses. Yet scientists know surprisingly little about these early changes. Reporting in Nature Communications, an international research team provides the most detailed accounting to date of the ... Read More