Gene therapy for hearing loss: Tag-teaming from the lab to the clinic
Two-year-old Miles is one of the first patients with hereditary hearing loss to receive gene therapy at Boston Children’s Hospital — to striking effect. In May 2025, Miles received an injection delivering a healthy copy of a gene called OTOF into the cochlea of his inner ear. Now, Miles is thriving. He’s had no adverse ... Read More about Gene therapy for hearing loss: Tag-teaming from the lab to the clinic
First-of-its-kind pressurization test could improve Ross procedure outcomes
The Ross procedure is a preferred surgery to treat severe aortic valve disease. The procedure replaces the failing valve with a patient’s own pulmonary valve. It’s an effective treatment option, but some patients have had complications. After surgery, the root of their aortic valve — where the valve connects with the heart — enlarges and causes ... Read More about First-of-its-kind pressurization test could improve Ross procedure outcomes
3D imaging could become standard practice in orthopedics. Here’s how.
It took a trained eye to see the abnormality on the patient’s X-ray. There, hidden behind the acetabulum was the shadow of a small bone spur. “At first glance, this looks like a normal, healthy hip,” says Young-Jo Kim, MD, PhD, director of the Child and Young Adult Hip Preservation Program at Boston Children’s Hospital. ... Read More about 3D imaging could become standard practice in orthopedics. Here’s how.
Promising advances in fetal therapy for vein of Galen malformation
In 2024, Megan Ingram* of California and her husband were preparing for the birth of their third child when a 34-week ultrasound revealed a potential complication. Their obstetrics team suspected a vein of Galen malformation (VOGM) — a rare vascular condition involving significantly elevated blood flow to the head because of direct connections between arteries ... Read More about Promising advances in fetal therapy for vein of Galen malformation
A case for Kennedy — and for rapid genomic testing in every NICU
Kennedy was born in August 2025 after what her parents, John and Diana, describe as an uneventful pregnancy. Soon after delivery, though, she struggled to breathe and feed. What followed was a series of hospital stays, a complex diagnosis, and a glimpse into how rapid genomic testing can deliver answers that guide critical decisions and ... Read More about A case for Kennedy — and for rapid genomic testing in every NICU
The hidden burden of solitude: How social withdrawal influences the adolescent brain
Adolescence is a period of social reorientation: a shift from a world centered on parents and family to one shaped by peers, schools, and broader networks. This expansion is critical for healthy development, but it also heightens susceptibility to social stressors. For some, those stressors trigger social withdrawal, a pull toward solitude that may alter ... Read More about The hidden burden of solitude: How social withdrawal influences the adolescent brain