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Your destination for kids' health

  • Forging a path back to school after orthopedic trauma

  • New genetic insights could change how we treat, and talk about, polycystic ovary syndrome

    Unveiling the hidden impact of moyamoya disease: Brain injury without symptoms

    A new druggable cancer target: RNA-binding proteins on the cell surface

A woman gazing out of a window.

Forecasting the future for childhood cancer survivors

Clinical, Research
Children are much more likely to survive cancer today than 50 years ago. Unfortunately, as adults, many of them develop cardiovascular disease, secondary cancers, or both, believed to result from the toxic effects of chemotherapy and radiation. But the full risk picture for survivors hasn’t been clear. “Patients want to know how long they’ll live ... Read More about Forecasting the future for childhood cancer survivors
Tagged: brain tumor, cancer, epidemiology, leukemia, research
A young child clutching her abdomen.

Genetic causes of congenital diarrhea and enteropathy come into focus

Clinical, Research
Congenital diarrheas and enteropathies are rare and devastating for infants and children. Treatments have consisted mainly of fluid and nutritional management. But in recent years, targeted dietary and drug therapies have emerged based on genetic discoveries. Now, research led by Boston Children’s Hospital, The Hospital for Sick Children in Toronto, and UCLA takes a major ... Read More about Genetic causes of congenital diarrhea and enteropathy come into focus
Tagged: gastroenterology, genetics and genomics, intestinal rehabilitation
A boy concentrates on his guitar fingering.

Genomic sequencing transforms a life: Asa’s story

Patient Stories, Research
Asa Cibelli feels like he’s been reborn. The straight-A middle schooler plays basketball and football, does jiu jitsu, is learning guitar, and can solve a Rubik’s cube in 40 seconds flat. But he once wondered if he’d ever feel better. From birth, Asa experienced chronic abdominal pain and severe diarrhea. The many doctors he saw ... Read More about Genomic sequencing transforms a life: Asa’s story
Tagged: gastroenterology, genetics and genomics, rare disease, research
MRI images of the falcine sinus with diameters of .36 cm and .96 cm

Could the falcine sinus hold the key to vein of Galen outcomes?

Clinical, Research
A Boston Children’s Hospital study uncovers how fetal magnetic resonance imaging (MRI) could be a game-changer in predicting outcomes for infants born with vein of Galen malformations (VOGMs). The study, just published in Stroke, focused on the width of the falcine sinus (FS) — the fetal structure that channels blood from the malformation back to ... Read More about Could the falcine sinus hold the key to vein of Galen outcomes?
Tagged: cerebrovascular surgery and interventions center, developmental milestones, nicu, pulmonary hypertension, research, vein of galen malformation
A brain with the thalamus highlighted, with signals radiating out from it.

The thalamus: A potential therapeutic target for neurodevelopmental disorders

Basic/Translational, Research
Years ago, as a neurology resident, Chinfei Chen, MD, PhD, cared for a 20-year-old woman who had experienced a very small stroke, affecting only the thalamus. “It was so tiny that she wouldn’t have noticed any symptoms had the stroke been in any other area of the brain,” says Chen, who is now an investigator ... Read More about The thalamus: A potential therapeutic target for neurodevelopmental disorders
Tagged: autism, developmental medicine, neurology, neuroscience
A large intestine with bacteria clustered around grapes, olives, almonds, a pear, and a kiwifruit.

Partnering diet and intestinal microbes to protect against GI disease

Basic/Translational, Research
Despite being an everyday necessity, nutrition is something of a black box. We know that many plant-based foods are good for us, but we don’t always know why. Our intestinal microbiome, which helps break down these foods once we consume them, is another black box. What role do our gut bacteria play? Seth Rakoff-Nahoum, MD, ... Read More about Partnering diet and intestinal microbes to protect against GI disease
Tagged: diet, gastroenterology, infectious diseases, inflammatory bowel disease, microbiome, nutrition

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