Archive for coronavirus
A new symptom of COVID-19 in young children: Croup
During the Omicron surge, pediatricians and emergency departments (EDs) began noticing something new: a surge in croup among infants and young children. Marked by a distinctive “barking” cough and sometimes noisy, high-pitched intakes of breath, croup can happen when colds and other viral infections cause the voice box, windpipe, and bronchial tubes to become inflamed ... Read More about A new symptom of COVID-19 in young children: Croup
Real-time genomic surveillance of bacteria could improve antibiotic therapy
Antibiotic-resistant bacterial infections are increasingly hard to treat, causing more than a million deaths annually around the world. Hospitalized patients with pneumonia, bloodstream infections, urinary tract infections, or abdominal infections are especially at risk. Like a game of Whac-A-Mole, bacteria can develop antibiotic resistance mutations within days of starting an antibiotic, only to be replaced ... Read More about Real-time genomic surveillance of bacteria could improve antibiotic therapy
Joining the fight against COVID: Women scientists at Boston Children’s are leading the way
When the COVID-19 pandemic hit in 2020, many women scientists around Boston Children’s pivoted to studying the new coronavirus and its effects. Today on the International Day of Women and Girls in Science, they offer their wisdom and advice on going into science, why they chose to do research on COVID-19, and the challenges they’ve ... Read More about Joining the fight against COVID: Women scientists at Boston Children’s are leading the way
A respiratory model of COVID-19, made from patients’ own cells
What happens in our respiratory tract once COVID-19 invades? A three-dimensional airway model, made from patient-derived stem cells, could provide answers about the initial stages of infection. The model not only replicates the infection process, but can be used to test potential antiviral drugs. Ruby Wang, MD, attending physician in Boston Children’s Division of Pulmonary ... Read More about A respiratory model of COVID-19, made from patients’ own cells
How to help young kids cope when a parent has to isolate
Parents: If you’ve tested positive for COVID-19 and need to isolate or quarantine, you understandably may have questions and concerns about what this means for your family. On top of coordinating logistics around work, child care, and safety measures, you may be worried about the psychological impact separation will have on your child. For children ... Read More about How to help young kids cope when a parent has to isolate
COVID-19 vaccination in 12- to 18-year-olds: What does the science say?
With a third “booster” dose of the Pfizer/BioNTech vaccine now authorized for children age 12 and older, you may be wondering about the safety and effectiveness of COVID-19 vaccination in teens. With months of experience — and recent research — to draw from, we now have more answers. Several recent studies led or co-led by ... Read More about COVID-19 vaccination in 12- to 18-year-olds: What does the science say?
Six tips for how families can manage Omicron
Omicron, a highly transmissible COVID-19 variant, is straining hospitals, canceling events, and emptying store shelves of test kits. It seems almost inevitable that it will find its way into households. Nearly two years into the pandemic, staying on top of COVID-19 guidance can seem exhausting. But you shouldn’t lose hope. Eventually, we will see the ... Read More about Six tips for how families can manage Omicron
Quarantining and isolating for COVID-19: Answers for families
Someone in your family has tested positive for COVID-19. You know you need to take steps to keep it from spreading — but just what does that involve? Here, we answer common questions about quarantine and isolation, based on guidance from the U.S. Centers for Disease Control and Prevention (CDC). What is “close contact”? Being ... Read More about Quarantining and isolating for COVID-19: Answers for families
From our labs and clinics: 10 research advances in 2021
Pediatric medicine at Boston Children’s Hospital rests on a strong base of discovery science. But it can take decades for bench discoveries to be validated and replicated in humans and for treatments to be proven safe. When lab discoveries advance on the road to clinical application, it’s cause to celebrate. Here are 10 research success ... Read More about From our labs and clinics: 10 research advances in 2021
From our labs and clinics: The top 10 COVID-19 science stories of 2021
As COVID-19 waxed, waned, morphed, and waxed again this year, research was taking place throughout Boston Children’s Hospital. Ongoing national studies the hospital is leading or co-leading include Overcoming COVID-19, a CDC-funded study on COVID-19 and multisystem inflammatory syndrome in children (MIS-C); IMPACC, examining immune responses in people hospitalized with COVID-19; and MUSIC, studying MISC’s ... Read More about From our labs and clinics: The top 10 COVID-19 science stories of 2021