Archive for neuroscience
The tiny choroid plexus protects the prenatal brain — but may also pass on inflammation from the mother
Floating in fluid deep in the brain are small, little-understood fronds of tissue. Two new studies reveal that these miniature organs are a hotbed of immune system activity. This activity may protect the developing brain from infections and other insults — but may also contribute to neurodevelopmental disorders like autism. Key takeaway This pioneering work ... Read More
Scar-free healing after spinal cord injury relies on specialized cells
Key takeaways Scar tissue prevents nerves from communicating with each other. Microglia cells in the central nervous system help prevent scar tissue formation after spinal cord injuries in newborn mice. Transplanted newborn microglia cells drastically reduced scar formation in adult mice with spinal cord injury, opening the door to new treatment possibilities. One of the ... Read More
Going into science: Women scientists at Boston Children’s offer advice to girls
In honor of the International Day of Women and Girls in Science (February 11), we invited women scientists at all stages of their careers at Boston Children’s Hospital to share their scientific agendas. Here is some of what they had to say. The scientists also offered their advice for girls interested in entering the field. ... Read More
The Beauty of the Brain
Every year, the Harvard Brain Science Initiative sponsors its Beauty of the Brain contest. This year, two Boston Children’s Hospital images are among the six winners drawn from a pool of forty submissions. Above, Mary Whitman, MD, PhD, and Jess Bell, from the laboratory of Elizabeth Engle, MD, developed this image of a developing mouse ... Read More
Internal brain timers linked with motivation and behavior
Time can be measured in many ways: a watch, a sundial, or the body’s natural circadian rhythms. But what about the sexual behavior of a fruit fly? “If you ask a bunch of scientists whether animals can keep time, many would say they cannot, that things happen over time—but time itself is not measured,” says ... Read More
Staff Spotlight: Meet Andrea Lerude
Andrea Lerude is a certified child life specialist on the inpatient neuroscience floor at Boston Children’s Hospital. She’s worked at Boston Children’s for more than five years. What does your job involve? As a child life specialist, I provide developmentally appropriate coping support to children in the hospital, in the form of play. Basically, I ... Read More
‘Face blindness’ may represent a failed brain network — and could shed light on autism
People with prosopagnosia, or “face blindness,” have trouble recognizing faces — even those of close friends and family members. While some people can compensate by using clothing and other cues, face blindness often creates serious social problems. It often becomes apparent in early childhood, but, rarely, people can acquire face blindness later in life after ... Read More
Two neuroscience rock stars elected to the National Academy of Medicine
Beth Stevens, PhD, and Elizabeth Engle, MD, are the latest Boston Children’s Hospital researchers to be elected to the prestigious National Academy of Medicine. Their election, together with Daphne Haas-Kogan, MD, brings Boston Children’s total number of current NAM members to 22. Both scientists hail from the F.M. Kirby Neurobiology Center at Boston Children’s and are ... Read More
Exploring autism by way of three rare genetic disorders
Rajna Filip-Dhima, MS is a senior project manager for the Translational Neuroscience Center at Boston Children’s Hospital and for the Developmental Synaptopathies Consortium, which just received a new cycle of NIH funding. Autism spectrum disorder (ASD) is now believed to affect 1 in 59 children in the U.S. Over the past five years, Boston Children’s Hospital ... Read More
Exploring an unsung part of the brain: the choroid plexus
If you’ve never heard of the choroid plexus, you’re not alone. In fact, few neuroscientists know much about this part of the brain. In the words of the late comedian Rodney Dangerfield, the choroid plexus “don’t get no respect.” But that’s beginning to change, thanks in part to Maria Lehtinen, PhD, who has made the ... Read More